TY - JOUR
T1 - Exposure to indoor tanning without burning and melanoma risk by sunburn history
AU - Vogel, Rachel Isaksson
AU - Ahmed, Rehana L.
AU - Nelson, Heather H.
AU - Berwick, Marianne
AU - Weinstock, Martin A.
AU - Lazovich, Deann
N1 - Funding Information:
This work was supported by the National Cancer Institute at the National Institutes of Health (5R01CA106807 and P30 CA77598) and the National Center for Advancing Translational Sciences of the National Institutes of Health (UL1TR000114).
PY - 2014/7/9
Y1 - 2014/7/9
N2 - Indoor tanning is carcinogenic to humans. Individuals report that they tan indoors before planning to be in the sun to prevent sunburns, but whether skin cancer is subsequently reduced is unknown. Using a population-based case-control study, we calculated the association between melanoma and indoor tanning after excluding exposed participants reporting indoor tanning-related burns, stratified by their number of lifetime sunburns (0, 1-2, 3-5, >5). Confounding was addressed using propensity score analysis methods. All statistical tests were two-sided. We observed increased risk of melanoma across all sunburn categories for participants who had tanned indoors without burning compared with those who never tanned indoors, including those who reported zero lifetime sunburns (odds ratio = 3.87; 95% confidence interval = 1.68 to 8.91; P =. 002). These data provide evidence that indoor tanning is a risk factor for melanoma even among persons who reported never experiencing burns from indoor tanning or outdoor sun exposure.
AB - Indoor tanning is carcinogenic to humans. Individuals report that they tan indoors before planning to be in the sun to prevent sunburns, but whether skin cancer is subsequently reduced is unknown. Using a population-based case-control study, we calculated the association between melanoma and indoor tanning after excluding exposed participants reporting indoor tanning-related burns, stratified by their number of lifetime sunburns (0, 1-2, 3-5, >5). Confounding was addressed using propensity score analysis methods. All statistical tests were two-sided. We observed increased risk of melanoma across all sunburn categories for participants who had tanned indoors without burning compared with those who never tanned indoors, including those who reported zero lifetime sunburns (odds ratio = 3.87; 95% confidence interval = 1.68 to 8.91; P =. 002). These data provide evidence that indoor tanning is a risk factor for melanoma even among persons who reported never experiencing burns from indoor tanning or outdoor sun exposure.
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U2 - 10.1093/jnci/dju219
DO - 10.1093/jnci/dju219
M3 - Article
C2 - 25031276
AN - SCOPUS:84905274860
SN - 0027-8874
VL - 106
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 7
M1 - dju219
ER -