TY - JOUR
T1 - Expression of EGFR and p53 in head and neck tumors among Sudanese patients
AU - Abusail, Mustafa S.aadalnour
AU - Dirweesh, Ahmed M.ohmed Ahmed
AU - Salih, Rashid A.wad Abdalla
AU - Gadelkarim, Ahmed H.ussain
PY - 2013/1/1
Y1 - 2013/1/1
N2 - BACKGROUND: The aim of this study was to assess EGFR and p53 expression in head and neck tumors among Sudanese patients using immunohistochemistry.MATERIALS AND METHODS: A retrospective descriptive study was performed on 150 samples from patients diagnosed with HNCs as well as 50 from individuals with benign head and neck tumors. EGFR and p53 expression was assessed using immunohistochemistry (IHC).RESULTS: EGFR was expressed in 126/150 (84%) of HNCS and 6/50 (12%) benign head and neck tumors where as p53 was expressed in 29/150 (19.3%) of HNCs and 2/50 (4%) of benign head and neck tumors, with significance at p values of 0.001 and 0.009 respectively.CONCLUSIONS: There is a significant association between EGFR, P53 expression and head and neck cancers among Sudanese patients.
AB - BACKGROUND: The aim of this study was to assess EGFR and p53 expression in head and neck tumors among Sudanese patients using immunohistochemistry.MATERIALS AND METHODS: A retrospective descriptive study was performed on 150 samples from patients diagnosed with HNCs as well as 50 from individuals with benign head and neck tumors. EGFR and p53 expression was assessed using immunohistochemistry (IHC).RESULTS: EGFR was expressed in 126/150 (84%) of HNCS and 6/50 (12%) benign head and neck tumors where as p53 was expressed in 29/150 (19.3%) of HNCs and 2/50 (4%) of benign head and neck tumors, with significance at p values of 0.001 and 0.009 respectively.CONCLUSIONS: There is a significant association between EGFR, P53 expression and head and neck cancers among Sudanese patients.
KW - EGFR
KW - Head and neck cancer
KW - P53
KW - Sudanese
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U2 - 10.7314/APJCP.2013.14.11.6415
DO - 10.7314/APJCP.2013.14.11.6415
M3 - Article
C2 - 24377543
AN - SCOPUS:85047687395
SN - 1513-7368
VL - 14
SP - 6415
EP - 6418
JO - Asian Pacific Journal of Cancer Prevention
JF - Asian Pacific Journal of Cancer Prevention
IS - 11
ER -
