Fatal infective endocarditis in a young adult with persistent truncus arteriosus and a bicuspid truncal valve

Persistent truncus arteriosus (TA) is usually fatal in infancy or early childhood. Almost all survivors beyond early childhood have severe elevation in pulmonary vascular resistance or have undergone a corrective surgical procedure.¹ Although infective endocarditis is associated with a variety of congenital cardiac abnormalities, it has rarely been reported with TA and has not been reported as a cause of death in any such patient.² Herein, we report a patient with TA who survived to age 19 years and died from infective endocarditis on a bicuspid truncal valve.