Feasibility, acceptability and preliminary efficacy of an online peer-to-peer social support ART adherence intervention

Keith J. Horvath, J. Michael Oakes, B. R. Simon Rosser, Gene Danilenko, Heather Vezina, K. Rivet Amico, Mark L. Williams, Jane Simoni

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

This study describes the results of an online social support intervention, called "Thrive with Me" (TWM), to improve antiretroviral therapy (ART) adherence. HIV-positive gay or bisexually-identified men self-reporting imperfect ART adherence in the past month were randomized to receive usual care (n = 57) or the eight-week TWM intervention (n = 67). Self-reported ART outcome measures (0-100 % in the past month) were collected at baseline, post-intervention, and 1-month follow-up. Follow-up assessment completion rate was 90 %. Participants rated (1-7 scale) the intervention high in information and system quality and overall satisfaction (Means ≥ 5.0). The intervention showed modest effects for the overall sample. However, among current drug-using participants, the TWM (vs. Control) group reported significantly higher overall ART adherence (90.1 vs. 57.5 % at follow-up; difference = 31.1, p = 0.02) and ART taken correctly with food (81.6 vs. 55.7 % at follow-up; difference = 47.9, p = 0.01). The TWM intervention appeared feasible to implement, acceptable to users, and demonstrated greatest benefits for current drug users.

Original languageEnglish (US)
Pages (from-to)2031-2044
Number of pages14
JournalAIDS and Behavior
Volume17
Issue number6
DOIs
StatePublished - Jul 2013

Keywords

  • Antiretroviral adherence
  • Internet-based intervention
  • Men who have sex with men
  • Social support

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