Fetal-Tissue Transplantation for Parkinson's Disease

Christopher G. Goetz; Richard D. Penn; Harold L. Klawans; John E. Van Gilder; Christopher H.k. Fung; James W. lo; Dennis D. Spencer; Kenneth L. Marek; D. Eugene Redmond; Curt R. Freed; Robert E. Breeze; Neil L. Rosenberg; Daniel J Garry; Arthur L. Caplan

doi:10.1056/NEJM199311113292013

Fetal-Tissue Transplantation for Parkinson's Disease

Christopher G. Goetz, Richard D. Penn, Harold L. Klawans, John E. Van Gilder, Christopher H.k. Fung, James W. lo, Dennis D. Spencer, Kenneth L. Marek, D. Eugene Redmond, Curt R. Freed, Robert E. Breeze, Neil L. Rosenberg, Daniel J Garry, Arthur L. Caplan

Medicine - Cardiology Division

Research output: Contribution to journal › Letter › peer-review

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Abstract

To the Editor: In their reports of the transplantation of fetal tissue in advanced Parkinson's disease (Nov. 26, 1992, issue), Spencer et al.¹ and Freed et al.² did not compare their results with those for adrenal transplantation. A detailed comparison cannot be made without a randomized, prospective trial, but patients receiving fetal transplants and those in the United Parkinson Foundation Registry on adrenal medullary transplantation³ had similar levels of function at base line, and both groups were evaluated with the Unified Parkinson's Disease Rating Scale (UPDRS). Adrenal transplantation was associated with more frequent and severe morbidity and longer hospital stays…

Original language	English (US)
Pages (from-to)	1498-1500
Number of pages	3
Journal	New England Journal of Medicine
Volume	329
Issue number	20
DOIs	https://doi.org/10.1056/NEJM199311113292013
State	Published - Nov 11 1993

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Goetz, C. G., Penn, R. D., Klawans, H. L., Van Gilder, J. E., Fung, C. H. K., lo, J. W., Spencer, D. D., Marek, K. L., Redmond, D. E., Freed, C. R., Breeze, R. E., Rosenberg, N. L., Garry, D. J., & Caplan, A. L. (1993). Fetal-Tissue Transplantation for Parkinson's Disease. New England Journal of Medicine, 329(20), 1498-1500. https://doi.org/10.1056/NEJM199311113292013

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title = "Fetal-Tissue Transplantation for Parkinson's Disease",

abstract = "To the Editor: In their reports of the transplantation of fetal tissue in advanced Parkinson's disease (Nov. 26, 1992, issue), Spencer et al.1 and Freed et al.2 did not compare their results with those for adrenal transplantation. A detailed comparison cannot be made without a randomized, prospective trial, but patients receiving fetal transplants and those in the United Parkinson Foundation Registry on adrenal medullary transplantation3 had similar levels of function at base line, and both groups were evaluated with the Unified Parkinson's Disease Rating Scale (UPDRS). Adrenal transplantation was associated with more frequent and severe morbidity and longer hospital stays…",

author = "Goetz, {Christopher G.} and Penn, {Richard D.} and Klawans, {Harold L.} and {Van Gilder}, {John E.} and Fung, {Christopher H.k.} and lo, {James W.} and Spencer, {Dennis D.} and Marek, {Kenneth L.} and Redmond, {D. Eugene} and Freed, {Curt R.} and Breeze, {Robert E.} and Rosenberg, {Neil L.} and Garry, {Daniel J} and Caplan, {Arthur L.}",

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AU - Goetz, Christopher G.

AU - Penn, Richard D.

AU - Klawans, Harold L.

AU - Van Gilder, John E.

AU - Fung, Christopher H.k.

AU - lo, James W.

AU - Spencer, Dennis D.

AU - Marek, Kenneth L.

AU - Redmond, D. Eugene

AU - Freed, Curt R.

AU - Breeze, Robert E.

AU - Rosenberg, Neil L.

AU - Garry, Daniel J

AU - Caplan, Arthur L.

PY - 1993/11/11

Y1 - 1993/11/11

N2 - To the Editor: In their reports of the transplantation of fetal tissue in advanced Parkinson's disease (Nov. 26, 1992, issue), Spencer et al.1 and Freed et al.2 did not compare their results with those for adrenal transplantation. A detailed comparison cannot be made without a randomized, prospective trial, but patients receiving fetal transplants and those in the United Parkinson Foundation Registry on adrenal medullary transplantation3 had similar levels of function at base line, and both groups were evaluated with the Unified Parkinson's Disease Rating Scale (UPDRS). Adrenal transplantation was associated with more frequent and severe morbidity and longer hospital stays…

AB - To the Editor: In their reports of the transplantation of fetal tissue in advanced Parkinson's disease (Nov. 26, 1992, issue), Spencer et al.1 and Freed et al.2 did not compare their results with those for adrenal transplantation. A detailed comparison cannot be made without a randomized, prospective trial, but patients receiving fetal transplants and those in the United Parkinson Foundation Registry on adrenal medullary transplantation3 had similar levels of function at base line, and both groups were evaluated with the Unified Parkinson's Disease Rating Scale (UPDRS). Adrenal transplantation was associated with more frequent and severe morbidity and longer hospital stays…

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Fetal-Tissue Transplantation for Parkinson's Disease

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