Flow-independent dynamics in aneurysms: Intra-aneurysm pressure measurements following complete flow cessation in internal carotid artery aneurysms

Adnan I. Qureshi, Mushtaq H. Qureshi, Tanya Mohindroo, Asif A. Khan, Kayla Dingmann, Gregory T. Sherr, M. Fareed K. Suri

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Purpose: To determine if complete flow obliteration by covered stents reduces intraaneurysm pressures in internal carotid artery (ICA) aneurysms.

Methods: A single lumen microcatheter was placed into the aneurysm sac prior to covered stent deployment in 3 patients and connected to a pressure monitoring system. The intraaneurysm pressure was continuously monitored, and readings were recorded prior to and immediately after stent deployment and at 5-minute intervals up to 20 minutes after stent placement. Complete occlusion of flow into the aneurysms was confirmed by carotid angiography.

Results: There was no change in mean pressure within the aneurysm before and immediately after stent placement (80 mmHg) in any patient, nor was there a change in waveform of the intra-aneurysm pressure recording. The average of intra-aneurysm pressures among the 3 patients was higher (99 mmHg) at 10 and 15 minutes after stent placement. In 2 patients, the microcatheter was retracted into the parent arterial lumen; no difference in pressure was noted.

Conclusion: Our observations suggest no change in the pressures within the aneurysm after complete flow cessation (flow-independent). These findings may assist clinicians in better understanding aneurysm hemodynamics and rupture after covered stent deployment.

Original languageEnglish (US)
Pages (from-to)861-866
Number of pages6
JournalJournal of Endovascular Therapy
Volume21
Issue number6
DOIs
StatePublished - Dec 1 2014

Keywords

  • Aneurysm
  • Aneurysm rupture
  • Aneurysm wall
  • Compliance
  • Covered stent
  • Hemodynamics
  • Internal carotid artery
  • Intra-aneurysm pressure
  • Intrasac pressure
  • Pressure transmission
  • Stent-graft

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