Fluorescence cystoscopy and bladder surveillance

Fadi N. Joudi, Badrinath R. Konety

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

Purpose of review: Update on new developments in the field of fluorescence cystoscopy. Recent findings: New agents are being studied to improve the accuracy of fluorescence cystoscopy. Hexyl-5-aminolevulinic acid is an ester form of 5-aminolevulinic acid with improved uptake by tumor cells. It has been shown to have higher specificity than 5-aminolevulinic acid and can possibly play a complementary role to standard cystoscopy. Hypericin is a promising new agent that has excellent sensitivity and specificity. The use of confocal microscopy to examine fluorescent tissue may help improve the accuracy. Summary: The addition of newer agents to the armamentarium of fluorescence cystoscopy has great potential with promising results in improving the diagnostic accuracy of bladder cancer and in particular carcinoma in situ. These agents need to be studied in large randomized trials to prove that using these agents can facilitate early diagnosis and improved prognosis in patients with bladder cancer.

Original languageEnglish (US)
Pages (from-to)265-270
Number of pages6
JournalCurrent Opinion in Urology
Volume14
Issue number5
DOIs
StatePublished - Sep 1 2004

Keywords

  • Bladder neoplasm
  • Cystoscopy
  • Fluorescence

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