TY - JOUR
T1 - Follow-up results in tuberculous cervical lymphadenitis
AU - Oktay, Mehmet F.
AU - Topcu, Ismail
AU - Senyigit, Abdurrahman
AU - Bilici, Aslan
AU - Arslan, Adem
AU - Cureoglu, Sebahattin
AU - Yildirim, Muzeyyen
PY - 2006/2
Y1 - 2006/2
N2 - Objective: To investigate the efficacy of medical antituberculous treatment in patients with tuberculous cervical lymphadenitis (TCL). Methods: In the period 1996-2002, 73 TCL patients were reviewed and the results of clinical and laboratory testing were documented. The efficacy of a four-drug chemotherapy regimen was investigated. Results: Purified protein derivatives (PPD) skin test results were positive in 58 (79 per cent) patients. Chest X-rays revealed changes consistent with tuberculosis in nine (12.3 per cent) patients. The mean duration of medical treatment was 10.04 months. In follow-up evaluation, 14 (20 per cent) patients were considered suspicious for resistant TCL and total excision of all nodes was performed. Histopathology confirmed TB in only 10 of these cases. Conclusion: The high incidence of residual disease in our study indicates that medical treatment (at least nine months of four combined antituberculous drugs) did not seem to be effective. If lymphadenopathy persists, total surgical excision of lymph nodes should be the treatment of choice.
AB - Objective: To investigate the efficacy of medical antituberculous treatment in patients with tuberculous cervical lymphadenitis (TCL). Methods: In the period 1996-2002, 73 TCL patients were reviewed and the results of clinical and laboratory testing were documented. The efficacy of a four-drug chemotherapy regimen was investigated. Results: Purified protein derivatives (PPD) skin test results were positive in 58 (79 per cent) patients. Chest X-rays revealed changes consistent with tuberculosis in nine (12.3 per cent) patients. The mean duration of medical treatment was 10.04 months. In follow-up evaluation, 14 (20 per cent) patients were considered suspicious for resistant TCL and total excision of all nodes was performed. Histopathology confirmed TB in only 10 of these cases. Conclusion: The high incidence of residual disease in our study indicates that medical treatment (at least nine months of four combined antituberculous drugs) did not seem to be effective. If lymphadenopathy persists, total surgical excision of lymph nodes should be the treatment of choice.
KW - Follow-Up Studies
KW - Lymph Nodes
KW - Mycobacterium Tuberculosis
KW - Neck
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U2 - 10.1017/S002221510500277X
DO - 10.1017/S002221510500277X
M3 - Article
C2 - 16359138
AN - SCOPUS:33746097437
SN - 0022-2151
VL - 120
SP - 129
EP - 132
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
IS - 2
ER -