Formation of tryptanthrin compounds upon Oxone-induced dimerization of indole-3-carbaldehydes

Amber C. Nelson, Emily S. Kalinowski, Taylor L. Jacobson, Peter Grundt

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Tryptanthrin is a natural product with numerous important pharmacological properties. Tryptanthrin and its analogs are commonly prepared by condensation of isatoic anhydride and isatin. In this Letter we investigate the formation of tryptanthrin derivatives upon Oxone-induced oxidative dimerization of indole-3-carbaldehydes.

Original languageEnglish (US)
Pages (from-to)6804-6806
Number of pages3
JournalTetrahedron Letters
Volume54
Issue number50
DOIs
StatePublished - Dec 11 2013

Bibliographical note

Funding Information:
This study was supported by funds from the University of Minnesota Undergraduate Research Program (UROP) and the NSF (Grant CHE-0922366 for X-ray diffractometer).

Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.

Keywords

  • Natural product synthesis
  • Oxidation
  • Tryptanthrin

Fingerprint Dive into the research topics of 'Formation of tryptanthrin compounds upon Oxone-induced dimerization of indole-3-carbaldehydes'. Together they form a unique fingerprint.

Cite this