Tryptanthrin is a natural product with numerous important pharmacological properties. Tryptanthrin and its analogs are commonly prepared by condensation of isatoic anhydride and isatin. In this Letter we investigate the formation of tryptanthrin derivatives upon Oxone-induced oxidative dimerization of indole-3-carbaldehydes.
Bibliographical noteFunding Information:
This study was supported by funds from the University of Minnesota Undergraduate Research Program (UROP) and the NSF (Grant CHE-0922366 for X-ray diffractometer).
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- Natural product synthesis