From sextant to GPS: Twenty-five years of mapping the genome with ChIP

David A. Wacker, Hoon Kim Tae

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Since its inception, ChIP technology has evolved immensely. Technological advances have improved its specificity and sensitivity, its scale has expanded to a genome-wide level, and its relative ease of use has made it a virtually ubiquitous tool. This year marks the 25th anniversary of the development of ChIP. In honor of this milestone, we briefly revisit its history, offer a review of recent articles employing ChIP on a genome-wide scale, and lay out our views for the future of ChIP.

Original languageEnglish (US)
Pages (from-to)6-10
Number of pages5
JournalJournal of Cellular Biochemistry
Volume107
Issue number1
DOIs
StatePublished - May 1 2009

Keywords

  • ChIP-chip
  • ChIP-pet
  • ChIP-sage
  • ChIP-seq
  • Genome-wide

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