TY - JOUR
T1 - Fungemia caused by Candida species in a children's public hospital in the city of São Paulo, Brazil
T2 - Study in the period 2007-2010
AU - Oliveira, Vanessa Kummer Perinazzo
AU - Ruiz, Luciana da Silva
AU - Oliveira, Nélio Alessandro Jesus
AU - Moreira, Débora
AU - Hahn, Rosane Christine
AU - Melo, Analy Salles de Azevedo
AU - Nishikaku, Angela Satie
AU - Paula, Claudete Rodrigues
PY - 2014
Y1 - 2014
N2 - Candidemia remains a major cause of morbidity and mortality in the health care environment. The epidemiology of Candida infection is changing, mainly in relation to the number of episodes caused by species C. non-albicans. The overall objective of this study was to evaluate the frequency of yeasts of the genus Candida, in a four-year period, isolated from blood of pediatric patients hospitalized in a public hospital of the city of São Paulo, Brazil. In this period, yeasts from blood of 104 patients were isolated and, the identified species of Candida by phenotypic and genotypic methods were: C. albicans (39/104), C. tropicalis (25/104), C. parapsilosis (23/104), Pichia anomala (6/104), C. guilliermondii (5/104), C. krusei (3/104), C. glabrata (2/104) and C. pararugosa (1/104). During the period of the study, a higher frequency of isolates of C. non-albicans (63.55%) (p = 0.0286) was verified. In this study we verified the increase of the non-albicans species throughout the years (mainly in 2009 and 2010). Thus, considering the peculiarities presented by Candida species, a correct identification of species is recommended to lead to a faster diagnosis and an efficient treatment.
AB - Candidemia remains a major cause of morbidity and mortality in the health care environment. The epidemiology of Candida infection is changing, mainly in relation to the number of episodes caused by species C. non-albicans. The overall objective of this study was to evaluate the frequency of yeasts of the genus Candida, in a four-year period, isolated from blood of pediatric patients hospitalized in a public hospital of the city of São Paulo, Brazil. In this period, yeasts from blood of 104 patients were isolated and, the identified species of Candida by phenotypic and genotypic methods were: C. albicans (39/104), C. tropicalis (25/104), C. parapsilosis (23/104), Pichia anomala (6/104), C. guilliermondii (5/104), C. krusei (3/104), C. glabrata (2/104) and C. pararugosa (1/104). During the period of the study, a higher frequency of isolates of C. non-albicans (63.55%) (p = 0.0286) was verified. In this study we verified the increase of the non-albicans species throughout the years (mainly in 2009 and 2010). Thus, considering the peculiarities presented by Candida species, a correct identification of species is recommended to lead to a faster diagnosis and an efficient treatment.
KW - Candida
KW - Candidemia
KW - Pediatric
UR - http://www.scopus.com/inward/record.url?scp=84905185348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84905185348&partnerID=8YFLogxK
U2 - 10.1590/S0036-46652014000400006
DO - 10.1590/S0036-46652014000400006
M3 - Article
C2 - 25076430
AN - SCOPUS:84905185348
SN - 0036-4665
VL - 56
SP - 301
EP - 305
JO - Revista do Instituto de Medicina Tropical de Sao Paulo
JF - Revista do Instituto de Medicina Tropical de Sao Paulo
IS - 4
ER -