TY - JOUR
T1 - Further comments on the lissencephaly syndromes.
AU - Dobyns, W. B.
AU - Gilbert, E. F.
AU - Opitz, J. M.
PY - 1985
Y1 - 1985
N2 - Detailed clinical, pathological, and cytogenetic investigations of patients with lissencephaly over the past several years have demonstrated the existence of at least eight distinct conditions with variable genetic implications. In several of these disorders, especially chromosomally normal MDS, ILS, and CCL, too few patients have been reported to permit citation of accurate recurrence risk figures. Accordingly, we wish to begin a registry of patients with lissencephaly of all types for the purpose of developing such risk figures and request that any available information be sent to one of us (W.B.D. or J.M.O.).
AB - Detailed clinical, pathological, and cytogenetic investigations of patients with lissencephaly over the past several years have demonstrated the existence of at least eight distinct conditions with variable genetic implications. In several of these disorders, especially chromosomally normal MDS, ILS, and CCL, too few patients have been reported to permit citation of accurate recurrence risk figures. Accordingly, we wish to begin a registry of patients with lissencephaly of all types for the purpose of developing such risk figures and request that any available information be sent to one of us (W.B.D. or J.M.O.).
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U2 - 10.1002/ajmg.1320220119
DO - 10.1002/ajmg.1320220119
M3 - Review article
C2 - 3901751
AN - SCOPUS:0022118788
SN - 0148-7299
VL - 22
SP - 197
EP - 211
JO - American Journal of Medical Genetics
JF - American Journal of Medical Genetics
IS - 1
ER -