TY - JOUR
T1 - Gastrointestinal cancer and the cystic fibrosis gene
AU - Audeh, M. William
AU - Neglia, Joseph P.
AU - Fitzsimmons, Stacey C.
AU - Lowenfels, Albert B.
PY - 1995/7/13
Y1 - 1995/7/13
N2 - To the Editor: Neglia et al. (Feb. 23 issue)1 report an increased incidence of gastrointestinal cancer in patients with cystic fibrosis and suggest a relation between the action of the defective gene and the development of cancer in the gastrointestinal tract. If this relation is confirmed, the gene for cystic fibrosis may be added to the growing list of genes conferring an increased risk of cancer and may be the first example of a more widespread biologic phenomenon: the role of evolutionary biology in cancer genetics. Since 1 in 25 to 50 white persons carries the gene for cystic fibrosis,. . .
AB - To the Editor: Neglia et al. (Feb. 23 issue)1 report an increased incidence of gastrointestinal cancer in patients with cystic fibrosis and suggest a relation between the action of the defective gene and the development of cancer in the gastrointestinal tract. If this relation is confirmed, the gene for cystic fibrosis may be added to the growing list of genes conferring an increased risk of cancer and may be the first example of a more widespread biologic phenomenon: the role of evolutionary biology in cancer genetics. Since 1 in 25 to 50 white persons carries the gene for cystic fibrosis,. . .
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U2 - 10.1056/NEJM199507133330214
DO - 10.1056/NEJM199507133330214
M3 - Letter
C2 - 7777028
AN - SCOPUS:0029038376
SN - 0028-4793
VL - 333
SP - 129
EP - 130
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 2
ER -
