Gastrointestinal cryptococcoma - Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?

Abdu K. Musubire; David B. Meya; Robert Lukande; Andrew Kambugu; Paul R. Bohjanen; David R. Boulware

doi:10.1016/j.mmcr.2015.03.004

Gastrointestinal cryptococcoma - Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?

Abdu K. Musubire, David B. Meya, Robert Lukande, Andrew Kambugu, Paul R. Bohjanen, David R. Boulware

Medicine - Infectious Disease and International

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis who presented with subacute, worsening abdominal pain during immune recovery. This evolved into chronic abdominal pain, with thickened bowel, and abdominal lymphadenopathy, while receiving empiric tuberculosis treatment. At 6-months, he developed intestinal perforation due to a histologically confirmed cryptococcoma.

Original language	English (US)
Pages (from-to)	40-43
Number of pages	4
Journal	Medical Mycology Case Reports
Volume	8
DOIs	https://doi.org/10.1016/j.mmcr.2015.03.004
State	Published - Jun 1 2015

Bibliographical note

Publisher Copyright:
© 2015 Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology.

Keywords

AIDS
Antiretroviral therapy
Cryptococcal meningitis
Cryptococcoma
HIV
Immune reconstitution inflammatory syndrome

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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@article{ded0f24b2cf04d5fa494778829809de5,

title = "Gastrointestinal cryptococcoma - Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?",

abstract = "The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis who presented with subacute, worsening abdominal pain during immune recovery. This evolved into chronic abdominal pain, with thickened bowel, and abdominal lymphadenopathy, while receiving empiric tuberculosis treatment. At 6-months, he developed intestinal perforation due to a histologically confirmed cryptococcoma.",

keywords = "AIDS, Antiretroviral therapy, Cryptococcal meningitis, Cryptococcoma, HIV, Immune reconstitution inflammatory syndrome",

author = "Musubire, {Abdu K.} and Meya, {David B.} and Robert Lukande and Andrew Kambugu and Bohjanen, {Paul R.} and Boulware, {David R.}",

note = "Publisher Copyright: {\textcopyright} 2015 Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology.",

year = "2015",

month = jun,

day = "1",

doi = "10.1016/j.mmcr.2015.03.004",

language = "English (US)",

volume = "8",

pages = "40--43",

journal = "Medical Mycology Case Reports",