Genetics of diabetic retinopathy

Satagopan Uthra; Rajiv Raman; Bickol N. Mukesh; Rani Padmaja Kumari; Tarun Sharma; Catherine A. McCarty; Govindasamy Kumaramanickavel

doi:10.1080/09723757.2008.11886027

Genetics of diabetic retinopathy

Satagopan Uthra, Rajiv Raman, Bickol N. Mukesh, Rani Padmaja Kumari, Tarun Sharma, Catherine A. McCarty, Govindasamy Kumaramanickavel

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Abstract

Diabetic retinopathy (DR), a microvascular complication of diabetes in the retina, is one of the leading causes of adult blindness worldwide. Complex interplay of environmental and genetic factors has been known to contribute to its pathology. Variations in several genes have been found to be associated with risk for developing DR in different populations worldwide, which is discussed in this article. Identification of genetic variations underlining the disease would immensely lead to recognition of presymptomatic diabetic individuals susceptible to develop DR and help in planning appropriate clinical management and genetic counseling of patients.

Original language	English (US)
Pages (from-to)	155-159
Number of pages	5
Journal	International Journal of Human Genetics
Volume	8
Issue number	1-2
DOIs	https://doi.org/10.1080/09723757.2008.11886027
State	Published - 2008

Keywords

Diabetic retinopathy
Gene-mapping
Genetic predisposition

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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abstract = "Diabetic retinopathy (DR), a microvascular complication of diabetes in the retina, is one of the leading causes of adult blindness worldwide. Complex interplay of environmental and genetic factors has been known to contribute to its pathology. Variations in several genes have been found to be associated with risk for developing DR in different populations worldwide, which is discussed in this article. Identification of genetic variations underlining the disease would immensely lead to recognition of presymptomatic diabetic individuals susceptible to develop DR and help in planning appropriate clinical management and genetic counseling of patients.",

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AU - Uthra, Satagopan

AU - Raman, Rajiv

AU - Mukesh, Bickol N.

AU - Kumari, Rani Padmaja

AU - Sharma, Tarun

AU - McCarty, Catherine A.

AU - Kumaramanickavel, Govindasamy

PY - 2008

Y1 - 2008

N2 - Diabetic retinopathy (DR), a microvascular complication of diabetes in the retina, is one of the leading causes of adult blindness worldwide. Complex interplay of environmental and genetic factors has been known to contribute to its pathology. Variations in several genes have been found to be associated with risk for developing DR in different populations worldwide, which is discussed in this article. Identification of genetic variations underlining the disease would immensely lead to recognition of presymptomatic diabetic individuals susceptible to develop DR and help in planning appropriate clinical management and genetic counseling of patients.

AB - Diabetic retinopathy (DR), a microvascular complication of diabetes in the retina, is one of the leading causes of adult blindness worldwide. Complex interplay of environmental and genetic factors has been known to contribute to its pathology. Variations in several genes have been found to be associated with risk for developing DR in different populations worldwide, which is discussed in this article. Identification of genetic variations underlining the disease would immensely lead to recognition of presymptomatic diabetic individuals susceptible to develop DR and help in planning appropriate clinical management and genetic counseling of patients.

KW - Diabetic retinopathy

KW - Gene-mapping

KW - Genetic predisposition

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Genetics of diabetic retinopathy

Abstract

Keywords

UN SDGs

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