Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for Subsequent Basal Cell Carcinoma

Y. Sapkota, Lucie M. Turcotte, Matthew J. Ehrhardt, Rebecca M. Howell, Michael A. Arnold, Carmen L. Wilson, W. Leisenring, Zhaoming Wang, Joshua Sampson, Casey L. Dagnall, Eric Karlins, Shengchao Alfred Li, Belynda D. Hicks, Rita Weathers, Susan A. Smith, Kyla Shelton, Qi Liu, Margaret A. Tucker, Stephen J. Chanock, Jinghui ZhangMelissa M. Hudson, Joseph P. Neglia, Gregory T. Armstrong, Leslie L. Robison, Lindsay M. Morton, S. Bhatia, Yutaka Yasui

Research output: Contribution to journalArticlepeer-review

14 Scopus citations
Original languageEnglish (US)
Pages (from-to)2042-2045.e8
JournalJournal of Investigative Dermatology
Volume139
Issue number9
DOIs
StatePublished - Sep 2019

Bibliographical note

Funding Information:
The Childhood Cancer Survivor Study (CCSS) genome-wide association study and pooled analyses were supported by the Division of Cancer Epidemiology and Genetics, Intramural Research Program of the National Cancer Institute , National Institutes of Health . This work used the computational resources of the National Institutes of Health High-Performance Computing Biowulf cluster ( http://hpc.nih.gov ). CCSS is supported by the National Cancer Institute (CA55727: GTA, principal investigator). A portion of the CCSS genotyping also was supported by the Leukemia and Lymphoma Society (K. Kamdar, principal investigator). The St. Jude Lifetime Cohort is supported by the National Cancer Institute ( U01 CA195547 : MMH and LLR, principal investigators; Cancer Center Support CORE grant CA21765: C. Roberts, principal investigator) and the American Lebanese Syrian Associated Charities (Memphis, TN). This study is also supported by R01 CA216354 (YY and JZ, principal investigators) from the National Cancer Institute.

Funding Information:
The Childhood Cancer Survivor Study (CCSS) genome-wide association study and pooled analyses were supported by the Division of Cancer Epidemiology and Genetics, Intramural Research Program of the National Cancer Institute, National Institutes of Health. This work used the computational resources of the National Institutes of Health High-Performance Computing Biowulf cluster (http://hpc.nih.gov). CCSS is supported by the National Cancer Institute (CA55727: GTA, principal investigator). A portion of the CCSS genotyping also was supported by the Leukemia and Lymphoma Society (K. Kamdar, principal investigator). The St. Jude Lifetime Cohort is supported by the National Cancer Institute (U01 CA195547: MMH and LLR, principal investigators; Cancer Center Support CORE grant CA21765: C. Roberts, principal investigator) and the American Lebanese Syrian Associated Charities (Memphis, TN). This study is also supported by R01 CA216354 (YY and JZ, principal investigators) from the National Cancer Institute. Conceptualization: YS, LLR, LMM, SB, YY; Data Curation: YS, LMT, MJE, RMH, MAA, CLW, WL, ZW, JS, CLD, EK, SAL, BDH, RW, SAS, KS, QL, MAT, SJC, JZ, MMH, JPN, GTA, LLR, LM, SB, YY; Formal Analysis: YS, LMT, JPN, MJE, MAA, JS, CLD, EK, SAL, BDH, MMH, GTA, LLR, LMM, YS, QL, YY; Investigation: YS, LMT, MJE, RMH, MAA, CLW, WL, ZW, JS, CLD, EK, SAL, BDH, RW, SAS, KS, QL, MAT, SJC, JZ, MMH, JPN, GTA, LLR, LM, SB, YY; Methodology: YS, LLR, LMM, SB, YY; Project Administration: YS, CLW, ZW, CLD, EK, SAL, BDH, MAT, SJC, MMH, GTA, LLR, LMM, SB, YY; Supervision: YS, LLR, LMM, SB, YY; Validation: YS, QL; Writing - Original Draft Preparation: YS, SB, YY; Writing - Review and Editing: YS, LMT, MJE, RMH, MAA, CLW, WL, ZW, JS, CLD, EK, SAL, BDH, RW, SAS, KS, QL, MAT, SJC, JZ, MMH, JPN, GTA, LLR, LM, SB, YY

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