Genome-wide patterns of genetic variation among elite maize inbred lines

Jinsheng Lai, Ruiqiang Li, Xun Xu, Weiwei Jin, Mingliang Xu, Hainan Zhao, Zhongkai Xiang, Weibin Song, Kai Ying, Mei Zhang, Yinping Jiao, Peixiang Ni, Jianguo Zhang, Dong Li, Xiaosen Guo, Kaixiong Ye, Min Jian, Bo Wang, Huisong Zheng, Huiqing LiangXiuqing Zhang, Shoucai Wang, Shaojiang Chen, Jiansheng Li, Yan Fu, Nathan M. Springer, Huanming Yang, Jian Wang, Jingrui Dai, Patrick S. Schnable, Jun Wang

Research output: Contribution to journalArticlepeer-review

333 Scopus citations

Abstract

We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.

Original languageEnglish (US)
Pages (from-to)1027-1030
Number of pages4
JournalNature Genetics
Volume42
Issue number11
DOIs
StatePublished - Nov 2010

Bibliographical note

Funding Information:
Supported by the 973 program (2009CB118400; 2007CB815703; 2007CB815705; 2007CB109000), the 863 project (2010AA10A106), the National Natural Science Foundation of China (30725008), the Shenzhen Bureau of Science Technology & Information, China (ZYC200903240077A; CXB200903110066A), the Chinese Academy of Science (GJHZ0701-6), the Ole Rømer grant from the Danish

Funding Information:
Natural Science Research Council and the US National Science Foundation (DBI-0527192). We thank L. Goodman for editing the manuscript.

Fingerprint Dive into the research topics of 'Genome-wide patterns of genetic variation among elite maize inbred lines'. Together they form a unique fingerprint.

Cite this