TY - JOUR
T1 - GRADE guidelines 26
T2 - informative statements to communicate the findings of systematic reviews of interventions
AU - GRADE Working Group
AU - Santesso, Nancy
AU - Glenton, Claire
AU - Dahm, Philipp
AU - Garner, Paul
AU - Akl, Elie A.
AU - Alper, Brian
AU - Brignardello-Petersen, Romina
AU - Carrasco-Labra, Alonso
AU - De Beer, Hans
AU - Hultcrantz, Monica
AU - Kuijpers, Ton
AU - Meerpohl, Joerg
AU - Morgan, Rebecca
AU - Mustafa, Reem
AU - Skoetz, Nicole
AU - Sultan, Shahnaz
AU - Wiysonge, Charles
AU - Guyatt, Gordon
AU - Schünemann, Holger J.
N1 - Publisher Copyright:
© 2019 The Authors
PY - 2020/3
Y1 - 2020/3
N2 - Objectives: Clear communication of systematic review findings will help readers and decision makers. We built on previous work to develop an approach that improves the clarity of statements to convey findings and that draws on Grading of Recommendations Assessment, Development and Evaluation (GRADE). Study Design and Setting: We conducted workshops including 80 attendants and a survey of 110 producers and users of systematic reviews. We calculated acceptability of statements and revised the wording of those that were unacceptable to ≥40% of participants. Results: Most participants agreed statements should be based on size of effect and certainty of evidence. Statements for low, moderate and high certainty evidence were acceptable to >60%. Key guidance, for example, includes statements for high, moderate and low certainty for a large effect on intervention x as: x results in a large reduction…; x likely results in a large reduction…; x may result in a large reduction…, respectively. Conclusions: Producers and users of systematic reviews found statements to communicate findings combining size and certainty of an effect acceptable. This article provides GRADE guidance and a wording template to formulate statements in systematic reviews and other decision tools.
AB - Objectives: Clear communication of systematic review findings will help readers and decision makers. We built on previous work to develop an approach that improves the clarity of statements to convey findings and that draws on Grading of Recommendations Assessment, Development and Evaluation (GRADE). Study Design and Setting: We conducted workshops including 80 attendants and a survey of 110 producers and users of systematic reviews. We calculated acceptability of statements and revised the wording of those that were unacceptable to ≥40% of participants. Results: Most participants agreed statements should be based on size of effect and certainty of evidence. Statements for low, moderate and high certainty evidence were acceptable to >60%. Key guidance, for example, includes statements for high, moderate and low certainty for a large effect on intervention x as: x results in a large reduction…; x likely results in a large reduction…; x may result in a large reduction…, respectively. Conclusions: Producers and users of systematic reviews found statements to communicate findings combining size and certainty of an effect acceptable. This article provides GRADE guidance and a wording template to formulate statements in systematic reviews and other decision tools.
KW - Evidence-based Medicine
KW - Health communication
KW - Language
KW - Persuasive communication
KW - Review literature as topic
KW - Surveys and Questionnaires
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U2 - 10.1016/j.jclinepi.2019.10.014
DO - 10.1016/j.jclinepi.2019.10.014
M3 - Article
C2 - 31711912
AN - SCOPUS:85076865412
SN - 0895-4356
VL - 119
SP - 126
EP - 135
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
ER -