Guanine-adenine DNA cross-linking by 1,2,3,4-diepoxybutane: Potential basis for biological activity

Chemical Compounds

• Mutation 50%
• Nucleobase 43%
• Bioactivity 43%
• Double-Stranded DNA 42%
• Adduct 42%
• Industrial Substance 26%
• Genotoxic 23%
• Smoke 22%
• Carcinogenic 21%
• Guanine 19%
• Adenine 18%
• Retention Time 18%
• Tandem Mass Spectrometry 16%
• Environmental Pollutant 16%
• Ultraviolet Spectrum 16%
• Metabolite 14%
• Substitution Reaction 12%
• Time 7%

Medicine & Life Sciences

• diepoxybutane 100%
• Guanine 71%
• Adenine 70%
• 2,3-butylene glycol 34%
• DNA 33%
• Yemen 30%
• 1,3-butadiene 15%
• 1,4-bis-(guan-7-yl)-2,3-butanediol 12%
• Base Pairing 10%
• High Pressure Liquid Chromatography 8%
• Vehicle Emissions 6%
• DNA Adducts 6%
• Sequence Deletion 5%
• Environmental Pollutants 5%
• Point Mutation 4%
• Chromosome Aberrations 4%
• Smoke 4%
• Tobacco Products 4%
• Mutation 2%