Harnessing cardiopulmonary interactions to improve circulation and outcomes after cardiac arrest and other states of low blood pressure

Anja K Metzger, Keith G Lurie

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Novel noninvasive technologies that harness the inherent physiological interactions between the heart, lungs, and brain have recently been shown to improve circulation and outcomes after cardiac arrest and other states of low blood pressure including hypovolemic shock. The impedance threshold devices (ResQPOD® and ResQGard®) and the intrathoracic pressure regulator (CirQlator™) are three new devices that create a negative intrathoracic pressure. The decrease in intrathoracic pressure creates a vacuum within the thorax relative to the rest of the body thereby enhancing venous blood return to the heart, increasing cardiac output and systemic arterial blood pressure, lowering right atrial and pulmonary artery pressures, lowering intracranial pressure, and increasing cerebral perfusion pressure. The animal and clinical data supporting the use of technologies that harness the intrathoraic pump are reviewed in this chapter.

Original languageEnglish (US)
Title of host publicationHandbook of Cardiac Anatomy, Physiology, and Devices
Subtitle of host publicationSecond Edition
PublisherHumana Press
Pages583-604
Number of pages22
ISBN (Print)9781588294432
DOIs
StatePublished - Dec 1 2005

Keywords

  • Active compression decompression CPR
  • Cardiac arrest
  • Cardiopulmonary resuscitation
  • Impedance threshold device
  • Intrathoracic pressure regulator

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