Heterologous helminth induced resistance to Ascaris suum in guinea pigs

Bert E. Stromberg, E. J.L. Soulsby

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The protection inducing capacity of Toxocara canis, Ancylostoma caninum, Haemonchus contortus, Caenorhabditis briggsae and Turbatrix aceti given via the mesenteric vein to a challenge infection with Ascaris suum was evaluated. Embryonated eggs and second stage larvae of T. canis and infective larvae of A. caninum were able to induce a statistically significant level of protective immunity, while the other non-related helminths were unable to protect against a challenge infection.

Original languageEnglish (US)
Pages (from-to)169-175
Number of pages7
JournalVeterinary Parasitology
Volume3
Issue number2
DOIs
StatePublished - Jun 1977

Bibliographical note

Funding Information:
The authors thank Dr T. Miller, Jensen-SalberyL aboratoriesK, ansasCity, Kansas, for the third stage larvae of A. caninum and Dr E.L. Hansen, Clinical PharmacologyR esearchI nstitute,Berkeley, California, for the C. briggsae. We also thank Miss Norma Molina and Mrs Rosetta Goss for their technical assistance. This work was supported in part by USPHS ResearchTrainingGrant AI-00302 and ResearchG rant AI-06262.

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