Hidden Complexity in Routine Adult and Pediatric Arrhythmias Interpretation: The Future of Precision Electrocardiology

Fabio M. Leonelli, Roberto De Ponti, Fabrizio Drago, Anwar Baban, Daniel Cortez, Massimo Griselli, Giuseppe Bagliani

Research output: Contribution to journalReview articlepeer-review

Abstract

Classic ECG interpretation is based on identification of waveforms and deductive analysis of the electrical events the waveforms represent. The more in depth the understanding of electrophysiologic cellular interactions, the more precise the interpretation of ECG tracing. Surface ECG has limitations; yet, it is accurate in representing myocytes’ pathologic behaviors. Recent advances have improved understanding of arrhythmias by reconstructing their mechanisms of induction and maintenance and exploring cellular channel dysfunction. Translating this knowledge to ECG analysis will create the link that allows ECG interpretation to reach the level of precision electrocardiology. This article presents cases illustrating new techniques for electrophysiologists.

Original languageEnglish (US)
Pages (from-to)391-404
Number of pages14
JournalCardiac Electrophysiology Clinics
Volume11
Issue number2
DOIs
StatePublished - Jun 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc.

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

Keywords

  • Arrhythmias
  • Channelopathies
  • ECG
  • Genetic testing
  • Precision electro cardiology

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