HIF hits Wnt in the stem cell niche

Dan S. Kaufman

Research output: Contribution to journalShort surveypeer-review

26 Scopus citations

Abstract

Distinct stem-cell populations are known to reside in hypoxic niches during development and postnatal life. Hypoxia-inducible transcription factors (HIFs) directly regulate the Wnt/β-catenin pathway to ensure the maintenance of both adult and embryonic stem cells.

Original languageEnglish (US)
Pages (from-to)926-927
Number of pages2
JournalNature Cell Biology
Volume12
Issue number10
DOIs
StatePublished - Oct 1 2010

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