High-throughput fabrication of plasmonic nanohole array sensors for label-free kinetic biosensing

Hyungsoon Im, Si Hoon Lee, Nathan J. Wittenberg, Timothy W. Johnson, Nathan C. Lindquist, Prashant Nagpal, David J. Norris, Sang Hyun Oh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this work, we demonstrate high-throughput fabrication of periodic metallic nanohole arrays in an almost centimeter square area through simple metal deposition and peeling off processes, called template stripping [1]. A thin silica layer is used to protect the template-stripped Ag nanoholes from unwanted oxidation and also to provide a robust surface on which lipid membranes can be formed. We also demonstrate label-free optical biosensing of molecular binding kinetics with the silica coated template-stripped nanohole arrays.

Original languageEnglish (US)
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages416-418
Number of pages3
StatePublished - Dec 1 2011
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: Oct 2 2011Oct 6 2011

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume1

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period10/2/1110/6/11

Keywords

  • Biosensing
  • Periodic nanohole array
  • Surface plasmon resonance
  • Template stripping

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