Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole

D. L. Larson; M. Sultana; A. E. Takemori; Philip S Portoghese

Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole

D. L. Larson, M. Sultana, A. E. Takemori, Philip S Portoghese

Medicinal Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Substitution of the cyclopropylmethyl group of the δ-opioid antagonist, naltrindole, and related compounds with other N-substituents (R = H or R = phenylethyl) afforded highly selective δ-opioid agonists.

Original language	English (US)
Title of host publication	New leads in opioid research
Subtitle of host publication	proceedings of the International Narcotics Research Conference. ICS914
Editors	J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
Publisher	Elsevier Science Publishers B.V.
Number of pages	1
ISBN (Print)	044481213X
State	Published - Jan 1 1990
Event	The International Narcotics Research Conference - Duration: Jul 8 1989 → Jul 13 1989

Publication series

Name	New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914

Other

Other	The International Narcotics Research Conference
Period	7/8/89 → 7/13/89

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Larson, D. L., Sultana, M., Takemori, A. E., & Portoghese, P. S. (1990). Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole. In J. M. Van Ree, A. H. Mulder, V. M. Wiegant, T. B. Van Wimersma Greidanus, J. M. Van Ree, A. H. Mulder, V. M. Wiegant, & T. B. Van Wimersma Greidanus (Eds.), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914 (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914). Elsevier Science Publishers B.V..

Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole. / Larson, D. L.; Sultana, M.; Takemori, A. E. et al.
New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. ed. / J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus; J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Larson, DL, Sultana, M, Takemori, AE & Portoghese, PS 1990, Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole. in JM Van Ree, AH Mulder, VM Wiegant, TB Van Wimersma Greidanus, JM Van Ree, AH Mulder, VM Wiegant & TB Van Wimersma Greidanus (eds), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914, Elsevier Science Publishers B.V., The International Narcotics Research Conference, 7/8/89.

Larson DL, Sultana M, Takemori AE, Portoghese PS. Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole. In Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, editors, New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Elsevier Science Publishers B.V. 1990. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

Larson, D. L. ; Sultana, M. ; Takemori, A. E. et al. / Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole. New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. editor / J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus ; J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

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abstract = "Substitution of the cyclopropylmethyl group of the δ-opioid antagonist, naltrindole, and related compounds with other N-substituents (R = H or R = phenylethyl) afforded highly selective δ-opioid agonists.",

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AU - Portoghese, Philip S

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A2 - Mulder, A.H.

A2 - Wiegant, V.M.

A2 - Van Wimersma Greidanus, T.B.

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A2 - Mulder, A.H.

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Highly selective nonpeptide delta-opioid receptor agonists related to naltrindole

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