Histoplasmosis among hospitalized febrile patients in northern Tanzania

Sarah M. Lofgren; Emily J. Kirsch; Venance P. Maro; Anne B. Morrissey; Levina J. Msuya; Grace D. Kinabo; Wilbrod Saganda; Helmut C. Diefenthal; Habib O. Ramadhani; L. Joseph Wheat; John A. Crump

doi:10.1016/j.trstmh.2012.05.009

Histoplasmosis among hospitalized febrile patients in northern Tanzania

Sarah M. Lofgren, Emily J. Kirsch, Venance P. Maro, Anne B. Morrissey, Levina J. Msuya, Grace D. Kinabo, Wilbrod Saganda, Helmut C. Diefenthal, Habib O. Ramadhani, L. Joseph Wheat, John A. Crump

Medicine - Infectious Disease and International

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Histoplasmosis may be common in East Africa but the diagnosis is rarely confirmed. We report 9 (0.9%) cases of probable histoplasmosis retrospectively identified among 970 febrile inpatients studied in northern Tanzania. Median (range) age was 31 (6, 44) years, 6 (67%) were female, 6 (67%) HIV-infected; 7 (78%) were clinically diagnosed with tuberculosis or bacterial pneumonia. Histoplasmosis is an important cause of febrile illness in Tanzania but is rarely considered in the differential diagnosis. Increased clinician awareness and availability of reliable diagnostic tests may improve patient outcomes.

Original language	English (US)
Pages (from-to)	504-507
Number of pages	4
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	106
Issue number	8
DOIs	https://doi.org/10.1016/j.trstmh.2012.05.009
State	Published - Aug 2012

Bibliographical note

Funding Information:
This research was supported by an International Studies on AIDS Associated Co-infections (ISAAC) award, a United States National Institutes of Health (NIH) funded program (U01 AI062563). Authors received support from NIH awards ISAAC (ABM, VPM, LJM, GDK, HOR, JAC); AIDS International Training and Research Program D43 PA-03-018 (ABM, VPM, HOR, JAC); the Duke Clinical Trials Unit and Clinical Research Sites U01 AI069484 (VPM, JAC), the Duke Center for AIDS Research P30 AI 64518 (L-YY, S-CC); the Center for HIV/AIDS Vaccine Immunology U01 AI067854 (JAC); and the Hubert-Yeargan Center for Global Health at Duke University (SML).

Keywords

Africa
HIV
Histoplasmosis
Tanzania
Tuberculosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Lofgren, S. M., Kirsch, E. J., Maro, V. P., Morrissey, A. B., Msuya, L. J., Kinabo, G. D., Saganda, W., Diefenthal, H. C., Ramadhani, H. O., Wheat, L. J., & Crump, J. A. (2012). Histoplasmosis among hospitalized febrile patients in northern Tanzania. Transactions of the Royal Society of Tropical Medicine and Hygiene, 106(8), 504-507. https://doi.org/10.1016/j.trstmh.2012.05.009

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Histoplasmosis among hospitalized febrile patients in northern Tanzania

Abstract

Bibliographical note

Keywords

UN SDGs

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