Histoplasmosis among hospitalized febrile patients in northern Tanzania

Sarah M. Lofgren, Emily J. Kirsch, Venance P. Maro, Anne B. Morrissey, Levina J. Msuya, Grace D. Kinabo, Wilbrod Saganda, Helmut C. Diefenthal, Habib O. Ramadhani, L. Joseph Wheat, John A. Crump

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Histoplasmosis may be common in East Africa but the diagnosis is rarely confirmed. We report 9 (0.9%) cases of probable histoplasmosis retrospectively identified among 970 febrile inpatients studied in northern Tanzania. Median (range) age was 31 (6, 44) years, 6 (67%) were female, 6 (67%) HIV-infected; 7 (78%) were clinically diagnosed with tuberculosis or bacterial pneumonia. Histoplasmosis is an important cause of febrile illness in Tanzania but is rarely considered in the differential diagnosis. Increased clinician awareness and availability of reliable diagnostic tests may improve patient outcomes.

Original languageEnglish (US)
Pages (from-to)504-507
Number of pages4
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume106
Issue number8
DOIs
StatePublished - Aug 2012

Keywords

  • Africa
  • HIV
  • Histoplasmosis
  • Tanzania
  • Tuberculosis

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