Although all agree that elevations in serum lipid levels are an integral part of the nephrotic syndrome, almost every other aspect of this secondary hyperlipidemia has been a source of controversy. The study reported by Joven et al. in this issue of the Journal 1 is one of many recent investigations that have attempted to answer several important questions, including the following: What specific lipoprotein abnormalities characterize patients with the nephrotic syndrome? Are the elevated levels of lipoprotein caused by increased production, decreased catabolism, or both? How does proteinuria cause hyperlipidemia? Does the hyperlipidemia in patients with the nephrotic syndrome cause.
Bibliographical noteFunding Information:
From the Division of Nephrology, Department of Medicine. l-eterans Administration Medical Center, Martinez. CA, and the University of California Davis School of Medicine. Davis, CA. Supported in part by the research service of the US l-eterans Administration. Address reprint requests to George A. Kaysen. MD, PhD, Chief of Nephrology, l-eterans Administration Medical Center. 150 Muir Rd, Martinez. CA 94553. © 1988 by the National Kidney Foundation, Inc. 0272-6386/881I206-0014$3.00/0
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