Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment

Amir Moheet; Christine L. Chan; Andrea Granados; Katie Larson Ode; Antoinette Moran; Alberto Battezzati

doi:10.1016/j.jcf.2019.08.004

Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment

Amir Moheet, Christine L. Chan, Andrea Granados, Katie Larson Ode, Antoinette Moran, Alberto Battezzati

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pathophysiology and impact of hypoglycemia, with a focus on people with cystic fibrosis. We will also review strategies to manage and prevent hypoglycemia.

Original language	English (US)
Pages (from-to)	S19-S24
Journal	Journal of Cystic Fibrosis
Volume	18
DOIs	https://doi.org/10.1016/j.jcf.2019.08.004
State	Published - Oct 2019

Bibliographical note

Funding Information:
AAM, CLC, AG, KLO and AM received grant support through the Cystic Fibrosis Foundation , Emerging Leaders in CF Endocrinology (EnVision) Program. The authors would like to thank the Cystic Fibrosis Foundation and the faculty mentor members of the EnVision Program , for their ongoing support and mentorship of the program awardees.

Publisher Copyright:
© 2019 European Cystic Fibrosis Society

Keywords

CFRD
Cystic fibrosis
Hypoglycemia
Reactive hypoglycemia

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't
Review

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1016/j.jcf.2019.08.004

OpenUrl availability

Full text

Cite this

@article{346a51750ad34ae09df7e8e43535a4ad,

title = "Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment",

abstract = "Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pathophysiology and impact of hypoglycemia, with a focus on people with cystic fibrosis. We will also review strategies to manage and prevent hypoglycemia.",

keywords = "CFRD, Cystic fibrosis, Hypoglycemia, Reactive hypoglycemia",

author = "Amir Moheet and Chan, {Christine L.} and Andrea Granados and Ode, {Katie Larson} and Antoinette Moran and Alberto Battezzati",

note = "Funding Information: AAM, CLC, AG, KLO and AM received grant support through the Cystic Fibrosis Foundation , Emerging Leaders in CF Endocrinology (EnVision) Program. The authors would like to thank the Cystic Fibrosis Foundation and the faculty mentor members of the EnVision Program , for their ongoing support and mentorship of the program awardees. Publisher Copyright: {\textcopyright} 2019 European Cystic Fibrosis Society",

year = "2019",

month = oct,

doi = "10.1016/j.jcf.2019.08.004",

language = "English (US)",

volume = "18",

pages = "S19--S24",

journal = "Journal of Cystic Fibrosis",

issn = "1569-1993",

publisher = "Elsevier",

}

TY - JOUR

T1 - Hypoglycemia in cystic fibrosis

T2 - Prevalence, impact and treatment

AU - Moheet, Amir

AU - Chan, Christine L.

AU - Granados, Andrea

AU - Ode, Katie Larson

AU - Moran, Antoinette

AU - Battezzati, Alberto

N1 - Funding Information: AAM, CLC, AG, KLO and AM received grant support through the Cystic Fibrosis Foundation , Emerging Leaders in CF Endocrinology (EnVision) Program. The authors would like to thank the Cystic Fibrosis Foundation and the faculty mentor members of the EnVision Program , for their ongoing support and mentorship of the program awardees. Publisher Copyright: © 2019 European Cystic Fibrosis Society

PY - 2019/10

Y1 - 2019/10

N2 - Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pathophysiology and impact of hypoglycemia, with a focus on people with cystic fibrosis. We will also review strategies to manage and prevent hypoglycemia.

AB - Hypoglycemia is a common and feared complication of insulin therapy. As in type 1 and type 2 diabetes, people with cystic fibrosis related diabetes are also at risk for hypoglycemia related to insulin therapy. Spontaneous hypoglycemia is also common in patients with CF without diabetes, who are not on glucose lowering medications. Spontaneous hypoglycemia in CF may also occur during or after an oral glucose tolerance test. In this review, we will discuss the definition, epidemiology, pathophysiology and impact of hypoglycemia, with a focus on people with cystic fibrosis. We will also review strategies to manage and prevent hypoglycemia.

KW - CFRD

KW - Cystic fibrosis

KW - Hypoglycemia

KW - Reactive hypoglycemia

UR - http://www.scopus.com/inward/record.url?scp=85073667068&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85073667068&partnerID=8YFLogxK

U2 - 10.1016/j.jcf.2019.08.004

DO - 10.1016/j.jcf.2019.08.004

M3 - Article

C2 - 31679723

AN - SCOPUS:85073667068

SN - 1569-1993

VL - 18

SP - S19-S24

JO - Journal of Cystic Fibrosis

JF - Journal of Cystic Fibrosis

ER -

Hypoglycemia in cystic fibrosis: Prevalence, impact and treatment

Abstract

Bibliographical note

Keywords

PubMed: MeSH publication types

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this