Hypoiodite mediated synthesis of isoxazolines from aldoximes and alkenes using catalytic KI and Oxone as the terminal oxidant

Akira Yoshimura, Chenjie Zhu, Kyle R. Middleton, Anthony D. Todora, Brent J. Kastern, Andrey V. Maskaev, Viktor Zhdankin

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

Isoxazolines can be efficiently synthesized in good yields via a hypoiodite mediated catalytic oxidative cyclization of aldoximes and alkenes. This reaction involves active iodine species generated in situ from catalytic amounts of KI and Oxone.

Original languageEnglish (US)
Pages (from-to)4800-4802
Number of pages3
JournalChemical Communications
Volume49
Issue number42
DOIs
StatePublished - Apr 30 2013

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