The aim of the study was to describe circadian hyper-amplitude-tension (CHAT) in an 82-year-old man treated with sotalol hydrochloride (Betapace), a beta-adrenoceptor blocker with class III anti-arrhythmic properties. Our results showed an increase in diastolic blood pressure, assessed as rhythm-adjusted mean value (MESOR), after treatment withdrawal and a decrease in both systolic and diastolic blood pressure (MESOR) after resuming treatment. This was accompanied by a considerable decrease in the double amplitude of both systolic and diastolic blood pressure.
|Original language||English (US)|
|Number of pages||4|
|Journal||Scripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae|
|State||Published - Dec 1 2003|
- Circadian variability
- Essential hypertension