TY - JOUR
T1 - Ideal cardiovascular health in young adult populations from the United States, Finland, and Australia and its association with cIMT
T2 - The international childhood cardiovascular cohort consortium
AU - Oikonen, Mervi
AU - Laitinen, Tomi T.
AU - Magnussen, Costan G.
AU - Steinberger, Julia
AU - Sinaiko, Alan R.
AU - Dwyer, Terence
AU - Venn, Alison
AU - Smith, Kylie J.
AU - Hutri-Kahonen, Nina
AU - Pahkala, Katja
AU - Mikkila, Vera
AU - Prineas, Ronald
AU - Viikari, Jorma S A
AU - Morrison, John A.
AU - Woo, Jessica G.
AU - Chen, Wei
AU - Nicklas, Theresa
AU - Srinivasan, Sathanur R.
AU - Berenson, Gerald
AU - Juonala, Markus
AU - Raitakari, Olli T.
PY - 2013
Y1 - 2013
N2 - Background--Goals for cardiovascular (CV) disease prevention were set by the American Heart Association in 2010 for the concept of CV health. Ideal CV health is defined by 7 CV health metrics: blood pressure, glucose, cholesterol, body mass index, and physical activity on recommended levels; nonsmoking; and a healthy diet. We studied the prevalence of ideal CV health and its associations with ultrasonographically measured carotid intima-media thickness (cIMT) cross-sectionally in 5 international populations. Methods and Results--Prevalence of ideal CV health was assessed among 5785 young adults (age, 36.6±3.2 years) comprising 335 participants from the Minneapolis Childhood Cohort Studies (Minnesota), 723 from the Princeton Follow-up Study, 981 from the Bogalusa Heart Study (BHS), 1898 from the Cardiovascular Risk in Young Finns Study (YFS), and 1848 from the Childhood Determinants of Adult Health Study (CDAH). Only 1% of the participants had all 7 ideal CV health metrics. The number of ideal CV health metrics associated inversely with cIMT in the 4 cohorts in which cIMT was available: for each additional ideal CV health metric, cIMT was 12.7 μm thinner in Minnesota (P=0.0002), 9.1 μm thinner in BHS (P=0.05), 10.4 lm thinner in YFS (P<0.0001), and 3.4 μm thinner in CDAH (P=0.03). Conclusions--The number of ideal CV health metrics was inversely associated with cIMT in the cohorts in which cIMT was available, indicating that ideal CV health metrics are associated with vascular health at the population level. Ideal CV health was rare in this large international sample of young adults, emphasizing the need for effective strategies for health promotion.
AB - Background--Goals for cardiovascular (CV) disease prevention were set by the American Heart Association in 2010 for the concept of CV health. Ideal CV health is defined by 7 CV health metrics: blood pressure, glucose, cholesterol, body mass index, and physical activity on recommended levels; nonsmoking; and a healthy diet. We studied the prevalence of ideal CV health and its associations with ultrasonographically measured carotid intima-media thickness (cIMT) cross-sectionally in 5 international populations. Methods and Results--Prevalence of ideal CV health was assessed among 5785 young adults (age, 36.6±3.2 years) comprising 335 participants from the Minneapolis Childhood Cohort Studies (Minnesota), 723 from the Princeton Follow-up Study, 981 from the Bogalusa Heart Study (BHS), 1898 from the Cardiovascular Risk in Young Finns Study (YFS), and 1848 from the Childhood Determinants of Adult Health Study (CDAH). Only 1% of the participants had all 7 ideal CV health metrics. The number of ideal CV health metrics associated inversely with cIMT in the 4 cohorts in which cIMT was available: for each additional ideal CV health metric, cIMT was 12.7 μm thinner in Minnesota (P=0.0002), 9.1 μm thinner in BHS (P=0.05), 10.4 lm thinner in YFS (P<0.0001), and 3.4 μm thinner in CDAH (P=0.03). Conclusions--The number of ideal CV health metrics was inversely associated with cIMT in the cohorts in which cIMT was available, indicating that ideal CV health metrics are associated with vascular health at the population level. Ideal CV health was rare in this large international sample of young adults, emphasizing the need for effective strategies for health promotion.
KW - Cardiovascular
KW - Carotid intima-media thickness
KW - Cohort studies
KW - Health behavior
UR - http://www.scopus.com/inward/record.url?scp=84888301784&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84888301784&partnerID=8YFLogxK
U2 - 10.1161/JAHA.113.000244
DO - 10.1161/JAHA.113.000244
M3 - Article
C2 - 23782922
AN - SCOPUS:84888301784
SN - 2047-9980
VL - 2
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 3
M1 - e000244
ER -