Abstract
HPLC-NMR, HPLC-MS, and HPLC-UV were used to characterize the predominant solution autoxidation and photodegradation products of ethynylestradiol (1). A hydroperoxide (2) and a series of isomeric dimeric oxidation products (3-7), were identified. (C) 2000 Elsevier Science B.V.
Original language | English (US) |
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Pages (from-to) | 927-937 |
Number of pages | 11 |
Journal | Journal of Pharmaceutical and Biomedical Analysis |
Volume | 23 |
Issue number | 5 |
DOIs | |
State | Published - Oct 2000 |
Keywords
- Autoxidation
- Estrogen
- Ethynylestradiol
- HPLC-MS
- HPLC-NMR
- Photodegradation