Idiopathic immune complex glomerulonephritis in dogs with multisystem involvement.

K. P. Jeraj, R. L. Vernier, D. Polzin, J. K. Klausner, C. A. Osborne, J. B. Stevens, A. F. Michael

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Renal specimens obtained by biopsy and/or at necropsy from 4 dogs with nephrotic syndrome were studied using light, immunofluorescence, and electron microscopies. The glomerulonephritis observed in these dogs was considered an idiopathic immune complex glomerulonephritis associated with multisystem involvement because causes of glomerulonephritis in these dogs could not be established. Immunoglobulin A was observed in granular deposits in the mesangial and subendothelial regions of the glomeruli. The relationship of the clinical and pathologic features of this disease in dogs to various renal syndromes in human beings are described.

Original languageEnglish (US)
Pages (from-to)1699-1705
Number of pages7
JournalAmerican journal of veterinary research
Volume45
Issue number9
StatePublished - Sep 1984

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