Abstract
Atherosclerosis is a chronic vascular disease affecting large and medium sized arteries. Several treatment options are already available for treatment of this disease. Targeting atherosclerotic plaques by high intensity focused ultrasound (HIFU) using dual mode ultrasound arrays (DMUA) was recently introduced in literature. We present a finite difference time domain (FDTD) simulation modeling of the wave propagation in heterogeneous medium from the surface of a 3.5MHz array prototype with 32-elements. After segmentation of the ultrasound image obtained for the treatment region in-vivo, we integrated this anatomical information into our simulation to account for different parameters that may be caused by these multi-region anatomical complexities. The simulation program showed that HIFU was able to induce damage in the prefocal region instead of the target area. The HIFU lesions, as predicted by our simulation, were well correlated with the actual damage detected in histology.
Original language | English (US) |
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Title of host publication | Proceedings from the 13th International Symposium on Therapeutic Ultrasound |
Editors | J. Brian Fowlkes, Vasant A. Salgaonkar |
Publisher | American Institute of Physics Inc. |
ISBN (Electronic) | 9780735414846 |
DOIs | |
State | Published - Mar 1 2017 |
Event | 13th International Symposium on Therapeutic Ultrasound, ISTU 2013 - Shanghai, China Duration: May 12 2013 → May 15 2013 |
Publication series
Name | AIP Conference Proceedings |
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Volume | 1816 |
ISSN (Print) | 0094-243X |
ISSN (Electronic) | 1551-7616 |
Other
Other | 13th International Symposium on Therapeutic Ultrasound, ISTU 2013 |
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Country/Territory | China |
City | Shanghai |
Period | 5/12/13 → 5/15/13 |
Bibliographical note
Publisher Copyright:© 2017 Author(s).