Imaging analysis of Bartonella species in the skin using single-photon and multi-photon (second harmonic generation) laser scanning microscopy

Azar Maluki, Edward Breitschwerdt, Lynne T Bemis, Rosalie Greenberg, Bobak Robert Mozayeni, Jamie Dencklau, Marna E Ericson

Research output: Contribution to journalArticlepeer-review


We demonstrate Bartonella spp are abundant in skin lesions resembling striae distensae. These striae distensae-like lesions, coincidental with sudden onset of neuropsychiatric symptoms, indicate testing for suspected Bartonella spp. infection.

Original languageEnglish (US)
Pages (from-to)1564-1570
Number of pages7
JournalClinical Case Reports
Issue number8
StatePublished - Aug 1 2020

Bibliographical note

Funding Information:
This work was done using single- and multi-photon laser scanning microscopes and staff support at the University of Minnesota Imaging Centers, Our thanks are extended to colleagues in Galaxy Diagnostics (Raleigh, NC) and in the Department of Dermatology at the University of Minnesota Medical School.

Publisher Copyright:
© 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd


  • Bartonella
  • confocal microscopy
  • psychiatric disorders
  • second harmonic generation
  • striae distensae

PubMed: MeSH publication types

  • Case Reports

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