TY - GEN
T1 - Imaging cellular microtubules with the atomic-force microscope
AU - Dixon Northern, Brenda L.
AU - Jordan, Mary A.
AU - Wilson, Leslie
AU - Zasadzinski, Joseph A.
PY - 1992
Y1 - 1992
N2 - We have immobilized chemically-fixed cellular microtubules and microtubule protein polymers on glow-discharged glass discs for scanning by atomic force microscopy (AFM). The images obtained by AFM resembled those obtained by conventional transmission electron microscopy of the same material. The AFM images can resolve some of the surface features of microtubules to 10 nm. Improvements in the techniques promise resolution approaching molecular dimensions.
AB - We have immobilized chemically-fixed cellular microtubules and microtubule protein polymers on glow-discharged glass discs for scanning by atomic force microscopy (AFM). The images obtained by AFM resembled those obtained by conventional transmission electron microscopy of the same material. The AFM images can resolve some of the surface features of microtubules to 10 nm. Improvements in the techniques promise resolution approaching molecular dimensions.
UR - http://www.scopus.com/inward/record.url?scp=0026441794&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026441794&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0026441794
SN - 0819407852
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 138
EP - 144
BT - Proceedings of SPIE - The International Society for Optical Engineering
PB - Publ by Int Soc for Optical Engineering
T2 - Scanning Probe Microscopies
Y2 - 20 January 1992 through 22 January 1992
ER -