Immunosuppression in Liver Transplantation

Aaron James Chan, John R Lake

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Acute and chronic liver diseases are dynamic processes causing numerous physiological and metabolic derangements. There are many supportive treatments for end-stage liver disease but the only definitive treatment is liver transplantation and the current effectiveness of liver transplantation, to a large extent, can be attributed to improvements in immunosuppression. This chapter describes a brief history of immunosuppression in liver transplantation, the rationale for immunosuppression, commonly used immunosuppression medications, common immunosuppressive regimens and unique circumstances that may require tailoring of medications. We also provide a brief introduction to future agents on the horizon.

Original languageEnglish (US)
Title of host publicationLiver Transplantation
Subtitle of host publicationClinical Assessment and Management
PublisherWiley Blackwell
Pages184-196
Number of pages13
ISBN (Electronic)9781118675915
ISBN (Print)9781118277386
DOIs
StatePublished - Jul 22 2013

Keywords

  • Immunosuppression
  • Liver
  • Transplant
  • Transplantation

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