Immunosuppression in Liver Transplantation

Aaron James Chan, John R Lake

Research output: Chapter in Book/Report/Conference proceedingChapter


Acute and chronic liver diseases are dynamic processes causing numerous physiological and metabolic derangements. There are many supportive treatments for end-stage liver disease but the only definitive treatment is liver transplantation and the current effectiveness of liver transplantation, to a large extent, can be attributed to improvements in immunosuppression. This chapter describes a brief history of immunosuppression in liver transplantation, the rationale for immunosuppression, commonly used immunosuppression medications, common immunosuppressive regimens and unique circumstances that may require tailoring of medications. We also provide a brief introduction to future agents on the horizon.

Original languageEnglish (US)
Title of host publicationLiver Transplantation
Subtitle of host publicationClinical Assessment and Management
PublisherWiley Blackwell
Number of pages13
ISBN (Electronic)9781118675915
ISBN (Print)9781118277386
StatePublished - Jul 22 2013


  • Immunosuppression
  • Liver
  • Transplant
  • Transplantation


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