Improved subtraction by adiabatic FAIR perfusion imaging

Janneke Schepers, Michael Garwood, Boudewijn Der Van Sanden, Klaas Nicolay

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

For pulsed arterial spin labeling techniques (e.g., FAIR), mismatches between the imaging and inversion slice profile result in a nonperfusion-related offset. Several methods have been proposed to reduce subtraction errors in FAIR imaging. Here an acquisition method for FAIR experiments based on adiabatic principles is proposed. It is shown that with adiabatic pulses the same pulse can be used for labeling and echo refocusing, thereby reducing the mismatch between imaging and labeling slice. A twofold reduction in subtraction errors compared to 5-lobe sinc excitation was shown both experimentally and by simulation. Magn Reson Med 47:2002.

Original languageEnglish (US)
Pages (from-to)330-336
Number of pages7
JournalMagnetic resonance in medicine
Volume47
Issue number2
DOIs
StatePublished - Feb 12 2002

Keywords

  • Adiabatic pulses
  • FAIR
  • Perfusion quantification
  • Spin labeling

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