Abstract
Efficiency in olefin cross-metathesis reactions is affected upon reducing the steric bulk of N-heterocyclic carbene ligands of ruthenium-based catalysts. For the formation of disubstituted olefins containing one or more allylic substituents, the catalyst bearing N-toiyl groups is more efficient than the corresponding N-mesityl catalyst. In contrast, the formation of trisubstituted olefins is more efficient using the W-mesitylcontaining catalyst. A hypothesis to explain this dichotomy is described.
Original language | English (US) |
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Pages (from-to) | 441-444 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 10 |
Issue number | 3 |
DOIs | |
State | Published - Feb 7 2008 |