Induction of hindlimb stepping movements in rats spinally transected as adults or as neonates

Robert L. Meisel, Brad Rakerd

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Rats were spinally transected as adults or as neonates. When their hindlimbs were held off the ground and tail pinch was applied, both groups of animals exhibited a strong tendency to step with alternating limbs. The most striking difference between the groups was in the rate of stepping, the neonatal spinals being significantly faster than the adult spinals. To our knowledge, this is the first evidence that adult-transected rats retain a degree of locomotion-related coordination.

Original languageEnglish (US)
Pages (from-to)353-356
Number of pages4
JournalBrain Research
Volume240
Issue number2
DOIs
StatePublished - May 27 1982
Externally publishedYes

Bibliographical note

Funding Information:
script. The research was supported by a USPHS Research Grant (HD-08933) to B. D. Sachs, and by

Funding Information:
a grant from the University of Connecticut Research Foundation.

Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.

Keywords

  • hindlimb coordination
  • locomotion
  • rat
  • spinal transection

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