Infection rates and treatment of low-velocity extremity gunshot injuries

Mai P. Nguyen, Jonathan C. Savakus, Jeffrey A. O'Donnell, Nicholas F. Prayson, Michael S. Reich, Joseph F. Golob, Amy A. Mcdonald, John J. Como, Heather A. Vallier

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Objectives: To determine the rates of infection in low-energy gunshot wounds (GSWs) to the extremity. Design: Retrospective review. Setting: Level I trauma center. Patients/Participants: Patients (N = 140) with at least 90-day follow-up for extremity-only low-energy GSW injuries from 2010-2014 were retrospectively reviewed. Treatment was recorded, including type and duration of antibiotics and details of nonoperative and operative managements. Main Outcome Measures: The rates of superficial and deep infections. Results: The overall infection rate was 15.7% (22 patients), and the deep infection rate was 3.6% (5 patients). Age, sex, and injury location were similar between the groups that did and did not receive antibiotic prophylaxis. Injury Severity Scores were higher in the group that did receive antibiotics. Regarding soft tissue-only injuries, antibiotic prophylaxis trended toward a lower rate of overall infection versus no antibiotic prophylaxis (6.1% vs. 25.9%, respectively, P = 0.07). Multiple doses of antibiotics did not reduce the rate of infection when compared with a single dose (14.6% vs. 12.5%, respectively, P = 1.00). No deep infections occurred in patients with nonoperatively treated fractures, regardless of antibiotic administration. All operatively treated fractures received antibiotic prophylaxis and demonstrated superficial and deep infection rates of 15.1% and 5.7%, respectively. Conclusions: Infections after low-energy extremity GSWs are infrequent. For soft tissue injuries without fracture, a single dose of intravenous antibiotics in the emergency department was associated with a lower rate of infection compared with no antibiotics. Operatively treated low-energy GSW fractures should receive standard perioperative antibiotics. Level of Evidence: Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.

Original languageEnglish (US)
Pages (from-to)326-329
Number of pages4
JournalJournal of orthopaedic trauma
Issue number6
StatePublished - Jun 1 2017
Externally publishedYes

Bibliographical note

Funding Information:
Supported by a research grant from AO North America.

Publisher Copyright:
© 2017 Wolters Kluwer Health, Inc.

Copyright 2017 Elsevier B.V., All rights reserved.


  • antibiotics
  • complication
  • fracture
  • gunshot
  • infection

Fingerprint Dive into the research topics of 'Infection rates and treatment of low-velocity extremity gunshot injuries'. Together they form a unique fingerprint.

Cite this