TY - GEN
T1 - Inferring network interactions using recurrent neural networks and swarm intelligence
AU - Ressom, Habtom W.
AU - Zhang, Yuji
AU - Xuan, Jianhua
AU - Wang, Yue
AU - Clarke, Robert
PY - 2006
Y1 - 2006
N2 - We present a novel algorithm combining artificial neural networks and swarm intelligence (SI) methods to infer network interactions. The algorithm uses ant colony optimization (ACO) to identify the optimal architecture of a recurrent neural network (RNN), while the weights of the RNN are optimized using particle swarm optimization (PSO). Our goal is to construct an RNN that mimics the true structure of an unknown network and the time-series data that the network generated. We applied the proposed hybrid SI-RNN algorithm to infer a simulated genetic network. The results indicate that the algorithm has a promising potential to infer complex interactions such as gene regulatory networks from time-series gene expression data.
AB - We present a novel algorithm combining artificial neural networks and swarm intelligence (SI) methods to infer network interactions. The algorithm uses ant colony optimization (ACO) to identify the optimal architecture of a recurrent neural network (RNN), while the weights of the RNN are optimized using particle swarm optimization (PSO). Our goal is to construct an RNN that mimics the true structure of an unknown network and the time-series data that the network generated. We applied the proposed hybrid SI-RNN algorithm to infer a simulated genetic network. The results indicate that the algorithm has a promising potential to infer complex interactions such as gene regulatory networks from time-series gene expression data.
UR - http://www.scopus.com/inward/record.url?scp=34047145502&partnerID=8YFLogxK
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U2 - 10.1109/IEMBS.2006.259812
DO - 10.1109/IEMBS.2006.259812
M3 - Conference contribution
C2 - 17946231
AN - SCOPUS:34047145502
SN - 1424400325
SN - 9781424400324
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 4241
EP - 4244
BT - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
T2 - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Y2 - 30 August 2006 through 3 September 2006
ER -