Abstract
Highly purified concanavalin A and other lectins injected in small amounts into the footpads of mice and rats induce an an intense and reproducible edema. Con A is eliminated from the site of injection at a slow rate, which may explain the prolonged nature of the inflammatory response it induces. Some advantages of the use of concanavalin A for the induction of experimental inflammation are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 590-593 |
| Number of pages | 4 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 146 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 1974 |
Bibliographical note
Funding Information:This investigation was supported by grant AI-10265 from The National Institutes of Health and by Contract NIH-NCI-72-3207 within the Special Virus-Cancer Program of NIH, US Public Health Service.