Abstract
Patients receiving >5 BT are more likely to display weak immune responsiveness, normal percentages of OKT 8 + T cells, and strong suppressor cell function in vitro. These immunologic traits may account for the beneficial effect of transfusions on graft survival. Phenotypic enumeration of OKT 8+ cells does not indicate suppressor function of these cells, since end-stage renal disease patients with normal OKT 8+ cells with >5 BT had greater suppressor function than those with <5 BT. These studies suggest that long-term evaluations of immune responsiveness may more accurately reflect influence of transfusions than isolated early posttransfusion testing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 335-337 |
| Number of pages | 3 |
| Journal | Transplantation Proceedings |
| Volume | 14 |
| Issue number | 2 |
| State | Published - Dec 1 1982 |