Interest in corneal wound healing has been fueled largely by the growth in surgical procedures including penetrating keratoplasty and refractive surgery. Recently, we have developed a collagen matrix designed to provide an important in vitro model for corneal wound healing. The matrix for this investigation was a porous collagen matrix composed of type I collagen from bovine corium supplemented with various proteoglycans. Results indicate that soluble factors produced by endothelial cells and insoluble factors produced by stromal fibroblasts influence epithelial layer formation on a collagen sponge.
|Original language||English (US)|
|Journal||Annals of Biomedical Engineering|
|Issue number||SUPPL. 1|
|State||Published - Dec 1 2000|
|Event||2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA|
Duration: Oct 12 2000 → Oct 14 2000