Influence of palmitic acid and hexadecanol on the phase transition temperature and molecular packing of dipalmitoylphosphatidyl-choline monolayers at the air-water interface

Ka Yee C. Lee, Ajaykumar Gopal, Anja Von Nahmen, Joseph A. Zasadzinski, Jaroslaw Majewski, Gregory S. Smith, Paul B. Howes, Kristian Kjaer

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The influence of hexadecanol (HD) and palmitic acid (PA) on the molecular packing and phase transition temperature of dipalmitoylphosphatidyl-choline (DPCC) monolayers was investigated at the air-water interfaces. The morphology and phase behavior of DPCC/HD monolayers and mixed DPCC/PA was determined by fluorescence microscopy and pressure-area-isotherms. The temperature of the liquid-expanded to condensed phase transition was increased by the addition of PA or HD to DPCC monolayers. The increase in amount of the single chain surfactant lead to a reduction in tilt angle of the aliphatic chains at a surface pressure of 40 mN/m.

Original languageEnglish (US)
Pages (from-to)774-783
Number of pages10
JournalJournal of Chemical Physics
Issue number2
StatePublished - Jan 8 2002
Externally publishedYes

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