Abstract
The structural and functional characteristics of the normal glomerular capillary wall are discussed in detail elsewhere in this text. For the purposes of this chapter, this discussion will focus on the major protein components of glomerular basement membrane (GBM): type IV collagen and laminin. The GBM contains specialized isoforms of these proteins which interact and form networks bridged by entactin/nidogen and heparan sulfate proteoglycans (agrin) [1–4].
Original language | English (US) |
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Title of host publication | Pediatric Nephrology, Seventh Edition |
Publisher | Springer Berlin Heidelberg |
Pages | 777-803 |
Number of pages | 27 |
ISBN (Electronic) | 9783662435960 |
ISBN (Print) | 9783662435953 |
DOIs | |
State | Published - Jan 1 2015 |