Inherited glomerular diseases

Michelle N Rheault, Clifford Kashtan

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

The structural and functional characteristics of the normal glomerular capillary wall are discussed in detail elsewhere in this text. For the purposes of this chapter, this discussion will focus on the major protein components of glomerular basement membrane (GBM): type IV collagen and laminin. The GBM contains specialized isoforms of these proteins which interact and form networks bridged by entactin/nidogen and heparan sulfate proteoglycans (agrin) [1–4].

Original languageEnglish (US)
Title of host publicationPediatric Nephrology, Seventh Edition
PublisherSpringer Berlin Heidelberg
Pages777-803
Number of pages27
ISBN (Electronic)9783662435960
ISBN (Print)9783662435953
DOIs
StatePublished - Jan 1 2015

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