Interaction of arachidonic acid and heme iron in the synthesis of prostaglandins.

Douglas A Peterson, J. M. Gerrard, G. H. Rao, E. L. Mills, J. G. White

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The reaction of ferrous iron and oxygen to oxidize arachidonic acid has been studied to aid in understanding the mechanism of PGG2 formation. Based on these results we have presented a novel concept of heme-arachidonic acid interaction in PG synthesis.

Original languageEnglish (US)
Pages (from-to)157-161
Number of pages5
JournalAdvances in prostaglandin and thromboxane research
Volume6
StatePublished - Jan 1 1980

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