Interpreting vital sign profiles for maximizing: Patient safety during dental visits

Frank J. Raab, Erwin M. Schaffer, Germaine G Cornelissen-Guillaume, Franz Halberg

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Concerns about local anesthetics and dental treatment stress are still prevalent in today's medical and dental communities. The authors conducted 24-hour monitoring of heart rate and blood pressure for 23 patients undergoing two root planing procedures and a single periodontal surgical procedure. Chronobiologic analysis of circadian blood pressure and heart rate rhythms revealed that neither epinephrine vasoconstrictor in anesthetics nor increased invasiveness of the procedure resulted in statistically significant deviations from regular, individualized blood pressure rhythms. For surgical appointments, time of day had the greatest effect on cardiovascular variables, with the greatest elevations in blood pressure seen for surgery at 8 a.m. and the largest blood pressure decreases seen for surgery at 2 p.m.

Original languageEnglish (US)
Pages (from-to)461-469
Number of pages9
JournalJournal of the American Dental Association
Issue number4
StatePublished - Apr 1998

Bibliographical note

Funding Information:
This research was supported by the University of Minnesota Clinical Dental Research Center (NIH/NIDR grant No. DE09737) and the University of Minnesota Chronobiology Research Center.

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