Intrapericardial Urokinase Irrigation and Systemic Corticosteroids: An Alternative to Pericardectomy for Persistent Fibrino-Purulent Pericarditis

M. Schafer, M. Lepori, A. Delabays, P. Ruchat, M. D. Schaller, Alain F Broccard

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

A 39-year-old man was admitted for upper abdominal pain and shortness of breath. The chest roentgenogram demonstrated cardiomegaly and left lower lobe atelectasis. Echocardiography showed circumferential pericardial effusion with signs of cardiac tamponade. Pericardial biopsy and fluid analysis were consistent with fibrino-purulent pericarditis. Despite broad-spectrum antibiotics, percutaneous and subsequently surgical drainage, pericardial effusion and tamponade recurred. We report successful treatment of a non-resolving fibrino-purulent pericardial effusion by combined intrapericardial irrigation of fibrinolytics and systemic corticosteroids administration as an alternative to pericardectomy.

Original languageEnglish (US)
Pages (from-to)508-511
Number of pages4
JournalVascular
Volume10
Issue number5
DOIs
StatePublished - Oct 2002
Externally publishedYes

Keywords

  • fibrinolysis
  • pericardiectomy
  • pericarditis
  • steroids

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